Fexofenadine Hydrochloride tablet is a predominant human and animal active metabolite of terfenadine. It is selective histamine H1-receptor antagonist. There has been no evidence of local anesthetic, analgesic, anticonvulsant, antidepressant, antidopaminergic, antiserotonergic, anticholinergic, sedative, H2-receptor antagonist, or a1-adrenergic receptor blocking activity.

Fexofenadine inhibits histamine induced skin wheal and flare responses. Following single and twice daily oral dose administration, antihistaminic effects occur within 1 hour, achieve a maximum at 6 hours, and last a minimum of 12 hours. There is no evidence of tolerance to these effects after 28 days of dosing.

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Adults and Children 12 years and older: The recommended dose is 60 mg twice daily.

A dose of 60 mg daily is recommended as a starting dose in individuals with decreased renal function.

Children under 12 years: Safety and effectiveness of fexofenadine in children under the age of 12 have not been established.

Each peach, round, double convex tablet, plain on one side and debossed on the other side with "60", contains fexofenadine HCl 60 mg. Nonmedicinal ingredients: croscarmellose sodium, gelatin, hydroxypropyl methylcellulose, lactose, magnesium stearate, microcrystalline cellulose, pink and yellow iron oxide blend, povidone, polyethylene glycol, silicon dioxide, starch and titanium dioxide. Blister packs of 12, 24 and 36.

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